TRUSTED: The Paired 3D Transabdominal Ultrasound and CT Human Data for Kidney Segmentation and Registration Research

Inter-modal image registration (IMIR) and image segmentation with abdominal Ultrasound (US) data has many important clinical applications, including image-guided surgery, automatic organ measurement and robotic navigation. However, research is severely limited by the lack of public datasets. We propose TRUSTED (the Tridimensional Renal Ultra Sound TomodEnsitometrie Dataset), comprising paired transabdominal 3DUS and CT kidney images from 48 human patients (96 kidneys), including segmentation, and anatomical landmark annotations by two experienced radiographers. Inter-rater segmentation agreement was over 94 (Dice score), and gold-standard segmentations were generated using the STAPLE algorithm. Seven anatomical landmarks were annotated, important for IMIR systems development and evaluation. To validate the dataset's utility, 5 competitive Deep Learning models for automatic kidney segmentation were benchmarked, yielding average DICE scores from 83.2% to 89.1% for CT, and 61.9% to 79.4% for US images. Three IMIR methods were benchmarked, and Coherent Point Drift performed best with an average Target Registration Error of 4.53mm. The TRUSTED dataset may be used freely researchers to develop and validate new segmentation and IMIR methods.Comment: Alexandre Hostettler, and Toby Collins share last authorshi

Memory transformers for full context and high-resolution 3D Medical Segmentation

International audienceTransformer models achieve state-of-the-art results for image segmentation. However, achieving long-range attention, necessary to capture global context, with high-resolution 3D images is a fundamental challenge. This paper introduces the Full resolutIoN mEmory (FINE) transformer to overcome this issue. The core idea behind FINE is to learn memory tokens to indirectly model full range interactions while scaling well in both memory and computational costs. FINE introduces memory tokens at two levels: the first one allows full interaction between voxels within local image regions (patches), the second one allows full interactions between all regions of the 3D volume. Combined, they allow full attention over high resolution images, e.g. 512 x 512 x 256 voxels and above. Experiments on the BCV image segmentation dataset shows better performances than state-of-the-art CNN and transformer baselines, highlighting the superiority of our full attention mechanism compared to recent transformer baselines, e.g. CoTr, and nnFormer

U-Net Transformer: Self and Cross Attention for Medical Image Segmentation

International audienceMedical image segmentation remains particularly challenging for complex and low-contrast anatomical structures. In this paper, we introduce the U-Transformer network, which combines a U-shaped architecture for image segmentation with self-and cross-attention from Transformers. U-Transformer overcomes the inability of U-Nets to model long-range contextual interactions and spatial dependencies, which are arguably crucial for accurate segmentation in challenging contexts. To this end, attention mechanisms are incorporated at two main levels: a self-attention module leverages global interactions between encoder features, while cross-attention in the skip connections allows a fine spatial recovery in the U-Net decoder by filtering out non-semantic features. Experiments on two abdominal CT-image datasets show the large performance gain brought out by U-Transformer compared to U-Net and local Attention U-Nets. We also highlight the importance of using both self-and cross-attention, and the nice interpretability features brought out by U-Transformer

U-Net Transformer: Self and Cross Attention for Medical Image Segmentation

International audienceMedical image segmentation remains particularly challenging for complex and low-contrast anatomical structures. In this paper, we introduce the U-Transformer network, which combines a U-shaped architecture for image segmentation with self-and cross-attention from Transformers. U-Transformer overcomes the inability of U-Nets to model long-range contextual interactions and spatial dependencies, which are arguably crucial for accurate segmentation in challenging contexts. To this end, attention mechanisms are incorporated at two main levels: a self-attention module leverages global interactions between encoder features, while cross-attention in the skip connections allows a fine spatial recovery in the U-Net decoder by filtering out non-semantic features. Experiments on two abdominal CT-image datasets show the large performance gain brought out by U-Transformer compared to U-Net and local Attention U-Nets. We also highlight the importance of using both self-and cross-attention, and the nice interpretability features brought out by U-Transformer